anti-CD81 antibody [2F7] (FITC)
CAT.NO. : ARG21037
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概述
产品描述 | FITC-conjugated Hamster Monoclonal antibody [2F7] recognizes CD81 |
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反应物种 | Ms |
应用 | BL, FACS, ICC/IF, IHC |
特异性 | Mouse CD81. The clone 2F7 can block thymocyte interaction with CD81 in vitro. |
宿主 | Hamster |
克隆 | Monoclonal |
克隆号 | 2F7 |
同位型 | IgG3 |
靶点名称 | CD81 |
抗原物种 | Mouse |
抗原 | Mouse epithelial cell line PAM212 |
偶联标记 | FITC |
別名 | CD antigen CD81; TAPA1; Tspan-28; S5.7; CD81 antigen; Target of the antiproliferative antibody 1; Tetraspanin-28; 26 kDa cell surface protein TAPA-1; CVID6; TSPAN28 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS and 0.1% Sodium azide. |
抗菌剂 | 0.1% Sodium azide |
浓度 | 0.5 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CD81 |
全名 | CD81 antigen |
背景介绍 | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
生物功能 | May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV. [UniProt] |
预测分子量 | 26 kDa |
翻译后修饰 | Not glycosylated. |
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