anti-CD85c / LILRB5 antibody
CAT.NO. : ARG42661
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概述
产品描述 | Rabbit Polyclonal antibody recognizes CD85c / LILRB5 |
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反应物种 | Hu |
预测物种 | Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CD85c / LILRB5 |
抗原物种 | Human |
抗原 | Synthetic peptide corresponding to aa. 128-173 of Human CD85c / LILRB5. |
偶联标记 | Un-conjugated |
別名 | LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; LIR-8; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; CD antigen CD85c; CD85C |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | THP-1 and MCF7 | ||||
实际分子量 | ~ 70 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
纯度 | > 95% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O75023 Human Leukocyte immunoglobulin-like receptor subfamily B member 5 |
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基因名称 | LILRB5 |
全名 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 |
背景介绍 | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
生物功能 | May act as receptor for class I MHC antigens. [UniProt] |
细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
预测分子量 | 64 kDa |
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