anti-CDC37 antibody [3G7]
![anti-CDC37 antibody [3G7]](/upload/image/products/ARG57075_WB_1_210_205.jpg)
![anti-CDC37 antibody [3G7]](/upload/image/products/ARG57075_WB_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57075
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [3G7] recognizes CDC37 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 3G7 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CDC37 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-378 of Human Cdc37. |
| 偶联标记 | Un-conjugated |
| 別名 | p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co-chaperone Cdc37; P50CDC37 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CDC37 |
| 全名 | cell division cycle 37 |
| 背景介绍 | The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008] |
| 生物功能 | Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. [UniProt] |
| 预测分子量 | 44 kDa |
| 翻译后修饰 | Constitutively sumoylated by UBE2I. |
检测图片 (1)
ARG57075 anti-CDC37 antibody [3G7] WB image
Western blot: 40 µg of 1) Jurkat cell lysate, 2) A431 cell lysate, 3) K562 cell lysate, 4) LnCap cell lysate, 5) SW480 cell lysate, 6) HeLa cell lysate, 7) MCF7 cell lysate, 8) 293T cell lysate stained with ARG57075 anti-CDC37 antibody [3G7] at 1:1000.
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