anti-CDC45 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG57313
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CDC45 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CDC45 |
| 抗原物种 | Human |
| 抗原 | Recombinant Protein of Human CDC45. |
| 偶联标记 | Un-conjugated |
| 別名 | Cell division control protein 45 homolog; CDC45L2; CDC45L; PORC-PI-1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HT-29 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O75419 Human Cell division control protein 45 homolog Swiss-port # Q9Z1X9 Mouse Cell division control protein 45 homolog |
|---|---|
| 基因名称 | CDC45 |
| 全名 | cell division cycle 45 |
| 背景介绍 | The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| 生物功能 | Required for initiation of chromosomal DNA replication. [UniProt] |
| 预测分子量 | 66 kDa |
检测图片 (1)
ARG57313 anti-CDC45 antibody WB image
Western blot: HT-29 cell lysate stained with ARG57313 anti-CDC45 antibody.
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