anti-CHD3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41829
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Size:
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CHD3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CHD3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human CHD3. |
| 偶联标记 | Un-conjugated |
| 別名 | Zinc finger helicase; Mi2-ALPHA; Chromodomain-helicase-DNA-binding protein 3; hZFH; Mi2-alpha; Mi-2a; Mi-2 autoantigen 240 kDa protein; ZFH; EC 3.6.4.12; ATP-dependent helicase CHD3; CHD-3 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | K562 | ||||||||||
| 实际分子量 | ~ 250 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q12873 Human Chromodomain-helicase-DNA-binding protein 3 |
|---|---|
| 基因名称 | CHD3 |
| 全名 | chromodomain helicase DNA binding protein 3 |
| 背景介绍 | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| 生物功能 | Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase and mitosis. [UniProt] |
| 预测分子量 | 227 kDa |
检测图片 (1)
ARG41829 anti-CHD3 antibody WB image
Western blot: K562 cell lysate stained with ARG41829 anti-CHD3 antibody.
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