anti-Claudin 3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58085
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Claudin 3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Claudin 3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human Claudin 3. |
| 偶联标记 | Un-conjugated |
| 別名 | CPE-R2; CPE-receptor 2; RVP1; HRVP1; CPE-R 2; CPETR2; hRVP1; C7orf1; Clostridium perfringens enterotoxin receptor 2; Rat ventral prostate.1 protein homolog; Claudin-3 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HT-29 | ||||||
| 实际分子量 | 21 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CLDN3 |
| 全名 | claudin 3 |
| 背景介绍 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [UniProt] |
| 细胞定位 | Cell junction, tight junction, Cell membrane, Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 23 kDa |
检测图片 (2)
ARG58085 anti-Claudin 3 antibody WB image
Western blot: 25 µg of HT-29 cell lysate stained with ARG58085 anti-Claudin 3 antibody at 1:400 dilution.
ARG58085 anti-Claudin 3 antibody ICC/IF image
Immunofluorescence: MCF7 cells stained with ARG58085 anti-Claudin 3 antibody at 1:100 dilution.
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