anti-CNOT4 antibody
CAT.NO. : ARG55215
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概述
产品描述 | Mouse Monoclonal antibody recognizes CNOT4 |
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反应物种 | Hu, Ms |
应用 | WB |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 343CT14.6.5 |
同位型 | IgG2a, kappa |
靶点名称 | CNOT4 |
抗原物种 | Human |
抗原 | Recombinant protein of Human CNOT4 (Swiss: O95628). |
偶联标记 | Un-conjugated |
別名 | CLONE243; NOT4; NOT4H; EC 6.3.2.-; CCR4-associated factor 4; Potential transcriptional repressor NOT4Hp; CCR4-NOT transcription complex subunit 4; E3 ubiquitin-protein ligase CNOT4 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse heart |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide |
抗菌剂 | 0.09% (W/V) Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O95628 Human CCR4-NOT transcription complex subunit 4 Swiss-port # Q8BT14 Mouse CCR4-NOT transcription complex subunit 4 |
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基因名称 | CNOT4 |
全名 | CCR4-NOT transcription complex, subunit 4 |
背景介绍 | The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010] |
生物功能 | Has E3 ubiquitin ligase activity. Involved in activation of the JAK/STAT pathway. [UniProt] |
细胞定位 | Cytoplasm. Nucleus |
研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
预测分子量 | 64 kDa |
翻译后修饰 | Autoubiquitinated. |
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