anti-CNTF antibody (Biotin)
CAT.NO. : ARG56822
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概述
产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes CNTF |
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反应物种 | Hu |
应用 | ELISA, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CNTF |
抗原物种 | Human |
抗原 | E.coli derived Recombinant Human CNTF. (AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTQSYVKH QGLNKNINLD SADGMPVAST DQWSQLTQAQ RLQQNLQAYR TFHVLLARLL QDQQVHFTPT QGDFHQAIHT LLLQVAAFAY QIQQLMILLQ YKIPRNQADG MPINVGDGGL FQKKLWGLKV LQQLSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM) |
偶联标记 | Biotin |
別名 | HCNTF; CNTF; Ciliary neurotrophic factor |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified by affinity chromatography. |
缓冲液 | PBS (pH 7.2) |
浓度 | 1 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CNTF |
全名 | ciliary neurotrophic factor |
背景介绍 | The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010] |
生物功能 | CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. [UniProt] |
预测分子量 | 23 kDa |
检测图片 (2)
ARG56822 anti-CNTF antibody (Biotin) standard curve image
Direct ELISA: ARG56822 anti-CNTF antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
ARG56822 anti-CNTF antibody (Biotin) standard curve image
Sandwich ELISA: ARG56822 anti-CNTF antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56713 anti-CNTF antibody as a capture antibody. Results of a typical standard run with optical density.
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