anti-Collagen I, alpha 1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG43821
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Collagen I, alpha 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IP, WB |
| 特异性 | Human |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Collagen I |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of human Collagen I. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Collagen alpha-1(I) chain |
| 別名 | COL1A1; Collagen Type I Alpha 1 Chain; OI4; Collagen, Type I, Alpha 1; Collagen Alpha-1(I) Chain; Alpha-1 Type I Collagen; Collagen Of Skin, Tendon And Bone, Alpha-1 Chain; Collagen Alpha-1(I) Chain Preproprotein; Type I Procollagen Alpha 1 Chain; Collagen Alpha 1 Chain Type I; Pro-Alpha-1 Collagen Type 1; Alpha1(I) Procollagen; Type I Proalpha 1; EDSARTH1; CAFYD; EDSC; OI1; OI2; OI3 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 139 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | Tris-Glycine, 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | COL1A1 |
| 全名 | Collagen Type I Alpha 1 Chain |
| 背景介绍 | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
| 生物功能 | Type I collagen is a member of group I collagen (fibrillar forming collagen). [UniProt] |
| 细胞定位 | Extracellular matrix, Secreted. [UniProt] |
| 预测分子量 | 139 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Hydroxylation, Phosphoprotein, Pyrrolidone carboxylic acid. [UniProt] |
检测图片 (2)
ARG43821 anti-Collagen I, alpha 1 antibody ICC/IF image
Immunofluorescence: Hela cells stained with ARG43821 anti-Collagen I, alpha 1 antibody at 1:50 dilution.
ARG43821 anti-Collagen I, alpha 1 antibody WB image
Western blot: A549, HL-60 and U2OS cells stained with ARG43821 anti-Collagen I, alpha 1 antibody at 1:1000 dilution.
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