anti-Collagen VII antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG64231
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Size:
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes Collagen VII |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms, Dog, Pig |
| 应用 | WB |
| 特异性 | This product does not work on cryostat sections of Normal Human Skin. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Collagen VII |
| 抗原物种 | Human |
| 抗原 | C-TVQYSDDPRTEF |
| 偶联标记 | Un-conjugated |
| 別名 | LC collagen; EBR1; VII; EBDCT; NDNC8; Collagen alpha-1; Long-chain collagen; EBD1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008] |
|---|---|
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 295 kDa |
| 翻译后修饰 | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. |
检测图片 (1)
ARG64231 anti-Collagen VII antibody WB image
Western blot: Rat testis lysate (35 µg protein in RIPA buffer) stained with ARG64231 anti-Collagen VII antibody at 0.5 µg/ml dilution.
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