anti-CST3 / Cystatin C antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes CST3 / Cystatin C
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CST3 / Cystatin C
  • 抗原物种: Human
  • 抗原: C-SVEEEGVRRALD
  • Brand:
CAT.NO. : ARG64901
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes CST3 / Cystatin C
反应物种Hu
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称CST3 / Cystatin C
抗原物种Human
抗原C-SVEEEGVRRALD
偶联标记Un-conjugated
別名Cystatin-C; Neuroendocrine basic polypeptide; Post-gamma-globulin; ARMD11; Cystatin-3; Gamma-trace
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1471 Human CST3

Swiss-port # P01034 Human Cystatin-C

背景介绍The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Developmental Biology antibody
预测分子量16 kDa
翻译后修饰The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
检测图片 (1)
  • ARG64901 anti-CST3 / Cystatin C antibody WB image

    Western blot: 35 µg of Human testis lysate (in RIPA buffer) stained with ARG64901 anti-CST3 / Cystatin C antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.

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