anti-CYP11B1 antibody
CAT.NO. : ARG44555
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概述
产品描述 | Rabbit Polyclonal antibody recognizes CYP11B1 |
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反应物种 | Hu |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CYP11B1 |
抗原物种 | Human |
抗原 | C-terminus of Human CYP11B1 |
偶联标记 | Un-conjugated |
別名 | CYP11B1; Cytochrome P450 Family 11 Subfamily B Member 1; P450C11; CPN1; FHI; Cytochrome P450, Subfamily XIB (Steroid 11-Beta-Hydroxylase), Polypeptide 1; Cytochrome P450, Family 11, Subfamily B, Polypeptide 1; Steroid 11-Beta-Hydroxylase, CYP11B1; Cytochrome P450 11B1, Mitochondrial; Steroid 11-Beta-Monooxygenase; Cytochrome P-450c11; Cytochrome P450C11; EC 1.14.15.4; CYP11B; Cytochrome P450 XIB1; EC 1.14.15; CYPXIB1; S11BH |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
稳定剂 | 5% BSA |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P15538 Human Cytochrome P450 11B1, mitochondrial |
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基因名称 | CYP11B1 |
全名 | Cytochrome P450 Family 11 Subfamily B Member 1 |
背景介绍 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] |
生物功能 | A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. |
细胞定位 | Membrane, Mitochondrion, Mitochondrion inner membrane |
预测分子量 | 58 kDa |
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