anti-Cytokeratin (pan) antibody [C-11]

产品描述: Mouse Monoclonal antibody [C-11] recognizes Cytokeratin (pan)
反应物种: Hu, Ms, Rat, Mamm
应用: CyTOF®-candidate, FACS, ICC/IF, IHC-P, IP, WB
特异性: The clone C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
宿主: Mouse
克隆: Monoclonal
克隆号: C-11
同位型: IgG1
靶点名称: Cytokeratin (pan)

CAT.NO. : ARG62969

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Size:

100 μg 50 μg

Product Details

概述

产品描述	Mouse Monoclonal antibody [C-11] recognizes Cytokeratin (pan)
反应物种	Hu, Ms, Rat, Mamm
应用	CyTOF®-candidate, FACS, ICC/IF, IHC-P, IP, WB
特异性	The clone C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
宿主	Mouse
克隆	Monoclonal
克隆号	C-11
同位型	IgG1
靶点名称	Cytokeratin (pan)
抗原物种	Human
抗原	Keratin-enriched preparation from human epidermoid carcinoma cell line A431.
偶联标记	Un-conjugated
別名	67 kDa cytokeratin; KRT1A; EPPK; Keratin, type II cytoskeletal 1; EHK1; K1; Keratin-1; CK1; Cytokeratin-1; Hair alpha protein; Type-II keratin Kb1; CK-1; NEPPK; EHK

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from ascites by protein-A affinity chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 16678 Mouse KRT1 GeneID: 300250 Rat KRT1 GeneID: 3848 Human KRT1 Swiss-port # P04104 Mouse Keratin, type II cytoskeletal 1 Swiss-port # P04264 Human Keratin, type II cytoskeletal 1 Swiss-port # Q6IMF3 Rat Keratin, type II cytoskeletal 1 More
基因名称	KRT1
全名	keratin 1, type II
背景介绍	Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
生物功能	May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. [UniProt]
产品亮点	Related Antibody Duos and Panels: ARG30319 Carcinoma / Sarcoma Antibody Duo Related products: Cytokeratin antibodies; Cytokeratin Duos / Panels; Anti-Mouse IgG secondary antibodies;
研究领域	Signaling Transduction antibody; Carcinoma Marker antibody
预测分子量	66 kDa
翻译后修饰	Undergoes deimination of some arginine residues (citrullination).

检测图片 (3)

ARG62969 anti-Cytokeratin (pan) antibody [C-11] WB image
Western blot: 30 µg of MCF-7 cell lysate stained with ARG62969 anti-Cytokeratin (pan) antibody [C-11] at 1:500 dilution.
ARG62969 anti-Cytokeratin (pan) antibody [C-11] ICC/IF image
Immunofluorescence: Rat endometrial epithelial (REE) cultured cells fixed with neutral buffered formalin for 10 min, and permeabilized with cold-methanol at -20°C for 10 min and then stained with ARG62969 anti-Cytokeratin (pan) antibody [C-11].
ARG62969 anti-Cytokeratin (pan) antibody [C-11] IHC-P image
Immunohistochemistry: Paraffin-embedded sections of guinea pig breast carcinoma stained with ARG62969 anti-Cytokeratin (pan) antibody [C-11].