anti-Cytokeratin (pan) antibody [C-11] (PE)
![anti-Cytokeratin (pan) antibody [C-11] (PE)](/upload/image/products/C-11_1_210_205.jpg)
![anti-Cytokeratin (pan) antibody [C-11] (PE)](/upload/image/products/C-11_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG53925
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Product Details
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [C-11] recognizes Cytokeratin (pan) |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mamm |
| 应用 | FACS |
| 特异性 | The clone C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | C-11 |
| 同位型 | IgG1 |
| 靶点名称 | Cytokeratin (pan) |
| 抗原物种 | Human |
| 抗原 | Keratin-enriched preparation from human epidermoid carcinoma cell line A431. |
| 偶联标记 | PE |
| 別名 | 67 kDa cytokeratin; KRT1A; EPPK; Keratin, type II cytoskeletal 1; EHK1; K1; Keratin-1; CK1; Cytokeratin-1; Hair alpha protein; Type-II keratin Kb1; CK-1; NEPPK; EHK |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KRT1 |
| 全名 | keratin 1, type II |
| 背景介绍 | Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. |
| 生物功能 | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. [UniProt] |
| 研究领域 | Signaling Transduction antibody; Carcinoma Marker antibody |
| 预测分子量 | 66 kDa |
| 翻译后修饰 | Undergoes deimination of some arginine residues (citrullination). |
检测图片 (1)
ARG53925 anti-Cytokeratin (pan) antibody [C-11] (PE) FACS image
Flow Cytometry: HT-29 cells stained with ARG53925 anti-Cytokeratin (pan) antibody [C-11] (PE).
Overlay with Isotype Mouse IgG1 control.
参考文献
克隆号文献
Intracellular distribution of p300 and its differential recruitment to aggresomes in breast cancer.
Establishment and characterization of baboon embryonic stem cell lines: an Old World Primate model for regeneration and transplantation research.
ICC/IF / Baboon
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