anti-DAAM1 antibody [5D3]
![anti-DAAM1 antibody [5D3]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG45062
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [5D3] recognizes DAAM1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5D3 |
| 同位型 | IgG2a |
| 靶点名称 | DAAM1 |
| 抗原物种 | Human |
| 抗原 | Clone 5D3 was generated from a recombinant protein that included amino acid residues from the N-terminal region of human DAAM1. This sequence has less than 50% homology to the N-terminal region of DAAM2. |
| 偶联标记 | Un-conjugated |
| 別名 | DAAM1; Dishevelled Associated Activator Of Morphogenesis 1; KIAA0666; Disheveled-Associated Activator Of Morphogenesis 1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8BPM0 Mouse Disheveled-associated activator of morphogenesis 1 Swiss-port # Q9Y4D1 Human Disheveled-associated activator of morphogenesis 1 |
|---|---|
| 基因名称 | DAAM1 |
| 全名 | Dishevelled Associated Activator Of Morphogenesis 1 |
| 背景介绍 | Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012] |
| 生物功能 | During cell division, may regulate RHOA activation that signals spindle orientation and chromosomal segregation. [Uniprot] |
| 细胞定位 | Cell projection, Cytoplasm, Cytoskeleton. [Uniprot] |
| 预测分子量 | 123 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
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