anti-DBNL / HIP55 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes DBNL / HIP55
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Dog
  • 应用: WB
  • 特异性: This antibody is expected to recognise all reported isoforms (NP_054782.2; NP_001014436.1; NP_001116428.1)
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DBNL / HIP55
  • Brand:
CAT.NO. : ARG63442
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes DBNL / HIP55
反应物种Hu
预测物种Ms, Rat, Dog
应用WB
特异性This antibody is expected to recognise all reported isoforms (NP_054782.2; NP_001014436.1; NP_001116428.1)
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称DBNL / HIP55
抗原物种Human
抗原AANLSRNGPALQE-C
偶联标记Un-conjugated
別名SH3P7; HIP55; SH3 domain-containing protein 7; ABP1; Cervical SH3P7; Drebrin-F; HPK1-interacting protein of 55 kDa; Drebrin-like protein; HIP-55; Cervical mucin-associated protein
应用说明
应用建议
应用推荐稀释比
WB0.03 - 0.1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 28988 Human DBNL

Swiss-port # Q9UJU6 Human Drebrin-like protein

基因名称DBNL
全名drebrin-like
生物功能Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. [UniProt]
研究领域Signaling Transduction antibody
预测分子量48 kDa
翻译后修饰Degraded by caspases during apoptosis.
检测图片 (2)
  • ARG63442 anti-DBNL / HIP55 antibody WB image

    Western blot: Jurkat lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63442 anti-DBNL / HIP55 antibody at 1 µg/ml dilution.

  • ARG63442 anti-DBNL / HIP55 antibody WB image

    Western blot: 35 µg of Human peripheral blood mononucleocyte lysate (in RIPA buffer) stained with ARG63442 anti-DBNL / HIP55 antibody at 0.03 µg/ml dilution and incubated at RT for 1 hour.

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