anti-DDX6 antibody
CAT.NO. : ARG41744
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概述
产品描述 | Rabbit Polyclonal antibody recognizes DDX6 |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | DDX6 |
抗原物种 | Human |
抗原 | Synthetic peptide within aa. 400 to the C-terminus of Human DDX6 (NP_001244120.1). |
偶联标记 | Un-conjugated |
別名 | Probable ATP-dependent RNA helicase DDX6; DEAD box protein 6; Oncogene RCK; ATP-dependent RNA helicase p54; EC 3.6.4.13; RCK; P54; HLR2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | Rat spleen | ||||||||
实际分子量 | ~ 54 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P26196 Human Probable ATP-dependent RNA helicase DDX6 Swiss-port # P54823 Mouse Probable ATP-dependent RNA helicase DDX6 |
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基因名称 | DDX6 |
全名 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
背景介绍 | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
生物功能 | In the process of mRNA degradation, may play a role in mRNA decapping. [UniProt] |
细胞定位 | Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Upon cellular stress, relocalizes to stress granules (PubMed:26184334). [UniProt] |
预测分子量 | 54 kDa |
翻译后修饰 | Sumoylated (PubMed:26184334). [UniProt] |
检测图片 (3)
ARG41744 anti-DDX6 antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG41744 anti-DDX6 antibody at 1:100 dilution.
ARG41744 anti-DDX6 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG41744 anti-DDX6 antibody at 1:100 dilution.
ARG41744 anti-DDX6 antibody WB image
Western blot: 25 µg of Rat spleen lysate stained with ARG41744 anti-DDX6 antibody at 1:1000 dilution.
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