anti-DISC1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes DISC1
  • 反应物种: Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DISC1
  • 抗原物种: Mouse
  • 抗原: DISC1 synthetic peptide containing amino acid residues from the C-terminus of mouse DISC1.This peptide sequence is well conserved in rat DISC1, but has 7 amino acid differences with the conserved site in human DISC1.
  • Brand:
CAT.NO. : ARG45064
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes DISC1
反应物种Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称DISC1
抗原物种Mouse
抗原DISC1 synthetic peptide containing amino acid residues from the C-terminus of mouse DISC1.
This peptide sequence is well conserved in rat DISC1, but has 7 amino acid differences with the conserved site in human DISC1.
偶联标记Un-conjugated
別名DISC1; DISC1 Scaffold Protein; Disrupted In Schizophrenia 1 Protein; Disrupted In Schizophrenia 1; C1orf136; KIAA0457; SCZD9
应用说明
应用建议
应用推荐稀释比
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Antigen Affinity Purified.
缓冲液PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA.
稳定剂50% Glycerol and 0.1 % BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 244667 Mouse DISC1

GeneID: 307940 Rat DISC1

Swiss-port # Q810H6 Rat Disrupted in schizophrenia 1 homolog

Swiss-port # Q811T9 Mouse Disrupted in schizophrenia 1 homolog

基因名称DISC1
全名DISC1 Scaffold Protein
背景介绍This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
生物功能Plays a role, together with PCNT, in the microtubule network formation. [Uniprot]
细胞定位Cytoplasm, Cytoskeleton, Microtubule, Mitochondrion, Synapse. [Uniprot]
预测分子量94 kDa
翻译后修饰Isopeptide bond, Ubl conjugation. [Uniprot]
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