anti-DLST antibody
CAT.NO. : ARG43835
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概述
产品描述 | Rabbit Polyclonal antibody recognizes DLST. |
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反应物种 | Hu |
应用 | ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Dihydrolipoamide S-Succinyltransferase |
抗原 | Recombinant fragment of human DLST (aa.188 - 453). |
偶联标记 | Un-conjugated |
別名 | DLST; Dihydrolipoamide S-Succinyltransferase; OGDC-E2; KGD2; DLTS; Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex, Mitochondrial; Dihydrolipoamide S-Succinyltransferase (E2 Component Of 2-Oxo-Glutarate Complex); 2-Oxoglutarate Dehydrogenase Complex Component E2; EC 2.3.1.61; E2K; Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex; Dihydrolipoyllysine-Residue Succinyltransferase; EC 2.3.1; PGL7 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified |
缓冲液 | Tris-Glycine (pH 7) with 0.01% Thimerosal |
抗菌剂 | 0.01% Thimerosal |
浓度 | 700 µg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P36957 Human Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarat |
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基因名称 | DLST |
全名 | Dihydrolipoamide S-Succinyltransferase |
背景介绍 | This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011] |
生物功能 | A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. |
细胞定位 | Mitochondrion, Nucleus |
翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (3)
ARG43835 anti-DLST antibody IHC-P image
Immunohistochemistry: Human carcinomastained with ARG43835 anti-DLST antibody at 1:500 dilution.
ARG43835 anti-DLST antibody WB image
Western blot: A431 stained with ARG43835 anti-DLST antibody at 1:1000 dilution.
ARG43835 anti-DLST antibody ICC/IF image
Immunofluorescence: A431 cells stained with ARG43835 anti-DLST antibody at 1:500 dilution.
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