anti-DRD2 / Dopamine Receptor D2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes DRD2 / Dopamine Receptor D2
  • 反应物种: Ms, Rat
  • 应用: ELISA, ICC/IF, IHC-Fr, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DRD2 / Dopamine Receptor D2
  • 抗原物种: Rat
  • 抗原: Synthetic peptide taken within aa. 150-200 from Rat DRD2 / Dopamine D2 receptor.
  • Brand:
CAT.NO. : ARG10779
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes DRD2 / Dopamine Receptor D2
反应物种Ms, Rat
应用ELISA, ICC/IF, IHC-Fr, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称DRD2 / Dopamine Receptor D2
抗原物种Rat
抗原Synthetic peptide taken within aa. 150-200 from Rat DRD2 / Dopamine D2 receptor.
偶联标记Un-conjugated
別名D2R; D2DR; D(2) dopamine receptor; Dopamine D2 receptor
应用说明
应用建议
应用推荐稀释比
ELISA1:50000
ICC/IF1:200
IHC-Fr1:200
IP1:200
WB1:1000 - 1:15000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂30% Glycerol and 0.5% BSA
浓度0.75 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 13489 Mouse DRD2

GeneID: 24318 Rat DRD2

Swiss-port # P61168 Mouse D(2) dopamine receptor

Swiss-port # P61169 Rat D(2) dopamine receptor

基因名称Drd2
全名dopamine receptor D2
背景介绍This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
生物功能Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. [UniProt]
预测分子量51 kDa
检测图片 (3)
  • ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody IHC-Fr image

    Immunohistochemistry: Mouse brain stained with ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody.

    From Nai-Li Wei et al. Neuropsychiatr Dis Treat. (2019), doi: 10.2147/NDT.S204818, Fig. S1.

  • ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody WB image

    Western blot: 1) Recombinant Dopamine D2 receptor protein, and 2) cerebellar membranes stained with ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody at 1:500 dilution.

  • ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody WB image

    Western blot: Rat striatal membranes stained with ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody at 1:500 dilution.

参考文献

Chronic stress increases susceptibility to food addiction by increasing the levels of DR2 and MOR in the nucleus accumbens.

IHC-Fr / Mouse

Wei Nai-Li et al.
Neuropsychiatr Dis Treat.,  (2019)

publication_link

 

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