anti-DRD2 / Dopamine Receptor D2 antibody
CAT.NO. : ARG10779
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概述
产品描述 | Rabbit Polyclonal antibody recognizes DRD2 / Dopamine Receptor D2 |
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反应物种 | Ms, Rat |
应用 | ELISA, ICC/IF, IHC-Fr, IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | DRD2 / Dopamine Receptor D2 |
抗原物种 | Rat |
抗原 | Synthetic peptide taken within aa. 150-200 from Rat DRD2 / Dopamine D2 receptor. |
偶联标记 | Un-conjugated |
別名 | D2R; D2DR; D(2) dopamine receptor; Dopamine D2 receptor |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 30% Glycerol and 0.5% BSA |
浓度 | 0.75 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | Drd2 |
全名 | dopamine receptor D2 |
背景介绍 | This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008] |
生物功能 | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. [UniProt] |
预测分子量 | 51 kDa |
检测图片 (3)
ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody IHC-Fr image
Immunohistochemistry: Mouse brain stained with ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody.
From Nai-Li Wei et al. Neuropsychiatr Dis Treat. (2019), doi: 10.2147/NDT.S204818, Fig. S1.
ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody WB image
Western blot: 1) Recombinant Dopamine D2 receptor protein, and 2) cerebellar membranes stained with ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody at 1:500 dilution.
ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody WB image
Western blot: Rat striatal membranes stained with ARG10779 anti-DRD2 / Dopamine Receptor D2 antibody at 1:500 dilution.
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