anti-F2R / PAR1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes F2R / PAR1
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: F2R / PAR1
  • 抗原物种: Human
  • 抗原: C-TRARRPESKATNAT
  • Brand:
CAT.NO. : ARG64922
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes F2R / PAR1
反应物种Hu
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称F2R / PAR1
抗原物种Human
抗原C-TRARRPESKATNAT
偶联标记Un-conjugated
別名CF2R; TR; Thrombin receptor; Proteinase-activated receptor 1; PAR1; Coagulation factor II receptor; PAR-1; HTR
应用说明
应用建议
应用推荐稀释比
IHC-PAssay - dependent
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2149 Human F2R

Swiss-port # P25116 Human Proteinase-activated receptor 1

背景介绍Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody
预测分子量47 kDa
翻译后修饰A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
Phosphorylated in the C-terminal tail; probably mediating desensitization prior to the uncoupling and internalization of the receptor.
检测图片 (2)
  • ARG64922 anti-F2R / PAR1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64922 anti-F2R / PAR1 antibody at 2.5 µg/ml dilution followed by AP-staining.

  • ARG64922 anti-F2R / PAR1 antibody WB image

    Western blot: 35 µg of HeLa cell lysate (in RIPA buffer) stained with ARG64922 anti-F2R / PAR1 antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.

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