anti-F2R / PAR1 antibody
CAT.NO. : ARG64922
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概述
产品描述 | Goat Polyclonal antibody recognizes F2R / PAR1 |
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反应物种 | Hu |
应用 | IHC-P, WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | F2R / PAR1 |
抗原物种 | Human |
抗原 | C-TRARRPESKATNAT |
偶联标记 | Un-conjugated |
別名 | CF2R; TR; Thrombin receptor; Proteinase-activated receptor 1; PAR1; Coagulation factor II receptor; PAR-1; HTR |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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背景介绍 | Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008] |
研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody |
预测分子量 | 47 kDa |
翻译后修饰 | A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. Phosphorylated in the C-terminal tail; probably mediating desensitization prior to the uncoupling and internalization of the receptor. |
检测图片 (2)
ARG64922 anti-F2R / PAR1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64922 anti-F2R / PAR1 antibody at 2.5 µg/ml dilution followed by AP-staining.
ARG64922 anti-F2R / PAR1 antibody WB image
Western blot: 35 µg of HeLa cell lysate (in RIPA buffer) stained with ARG64922 anti-F2R / PAR1 antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.
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