anti-FECH antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes FECH
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FECH
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 1-200 of Human FECH (NP_000131.2).
  • Brand:
CAT.NO. : ARG58667
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes FECH
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称FECH
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 1-200 of Human FECH (NP_000131.2).
偶联标记Un-conjugated
別名EPP; EC 4.99.1.1; Ferrochelatase, mitochondrial; FCE; Protoheme ferro-lyase; Heme synthase
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:100
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse brain
实际分子量50 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2235 Human FECH

Swiss-port # P22830 Human Ferrochelatase, mitochondrial

基因名称FECH
全名ferrochelatase
背景介绍The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]
生物功能Catalyzes the ferrous insertion into protoporphyrin IX. [UniProt]
细胞定位Mitochondrion inner membrane, Peripheral membrane protein, Matrix side. [UniProt]
预测分子量48 kDa
检测图片 (2)
  • ARG58667 anti-FECH antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human stomach stained with ARG58667 anti-FECH antibody at 1:100 dilution.

  • ARG58667 anti-FECH antibody WB image

    Western blot: 25 µg of Mouse brain lysate stained with ARG58667 anti-FECH antibody at 1:1000 dilution.

参考文献

The Effect of Photodynamic Therapy Using 5-Aminolevulinic Acid in Bone and Soft Tissue Sarcoma Cells

WB / Human,Mouse

Ryohei Adachi et al.
Anticancer Res.,  (2024)

publication_link

 

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