anti-FGFBP1 antibody
CAT.NO. : ARG44661
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概述
产品描述 | Mouse Monoclonal antibody recognizes FGFBP1 |
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反应物种 | Hu |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG2b |
靶点名称 | FGFBP1 |
抗原物种 | Human |
偶联标记 | Un-conjugated |
別名 | FGFBP1; Fibroblast Growth Factor Binding Protein 1; HBP17; FGFBP; 17 KDa Heparin-Binding Growth Factor-Binding Protein; Fibroblast Growth Factor-Binding Protein 1; 17 KDa HBGF-Binding Protein; FGF-Binding Protein 1; FGF-BP1; FGFBP-1; FGF-BP; Heparin-Binding Growth Factor Binding Protein; HBp17 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q14512 Human Fibroblast growth factor-binding protein 1 |
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基因名称 | FGFBP1 |
全名 | Fibroblast Growth Factor Binding Protein 1 |
背景介绍 | This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011] |
生物功能 | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. [UniProt] |
细胞定位 | Cell membrane, Membrane, Secreted. [UniProt] |
预测分子量 | 26 kDa |
翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (3)
ARG44661 anti-FGFBP1 antibody IHC-P image
Immunohistochemistry: Human Tonsilstained with ARG44661 anti-FGFBP1 antibody at 7.5 µg/mL dilution.
ARG44661 anti-FGFBP1 antibody WB image
Western blot: A431 stained with ARG44661 anti-FGFBP1 antibody at 1 µg/mL dilution.
ARG44661 anti-FGFBP1 antibody IP image
Immunoprecipitation: A431 lysate immunoprecipitated with 2.5 µg of ARG44661 anti-FGFBP1 antibody.
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