anti-FH / Fumarase antibody [3F6]

CAT.NO. : ARG57146

US＄ Please choose

Size:

50 μl

Product Details

概述

产品描述	Mouse Monoclonal antibody [3F6] recognizes FH / Fumarase
反应物种	Hu
应用	FACS, ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	3F6
同位型	IgG2a, kappa
靶点名称	FH / Fumarase
抗原物种	Human
抗原	Recombinant fragment around aa. 44-510 of Human FH / Fumarase
偶联标记	Un-conjugated
別名	MCUL1; MCL; LRCC; EC 4.2.1.2; Fumarate hydratase, mitochondrial; FMRD; Fumarase; HLRCC

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 2271 Human FH Swiss-port # P07954 Human Fumarate hydratase, mitochondrial
基因名称	FH
全名	fumarate hydratase
背景介绍	The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
生物功能	Also acts as a tumor suppressor. [UniProt]
产品亮点	Related products: Fumarase antibodies; Fumarase ELISA Kits; Anti-Mouse IgG secondary antibodies; Related news: TCA intermediate fumarate promotes mitobiogenesis
预测分子量	55 kDa

检测图片 (2)

ARG57146 anti-FH / Fumarase antibody [3F6] FACS image
Flow Cytometry: HeLa cell line stained with ARG57146 anti-FH / Fumarase antibody [3F6] at 2-5 µg for 1x10^6 cells. Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate.
ARG57146 anti-FH / Fumarase antibody [3F6] WB image
Western blot: 40 µg of 1) HeLa, 2) LNCap, 3) A549, 4) HepG2, 5) 293T, 6) K562, and 7) Jurkat cell lysates stained with ARG57146 anti-FH / Fumarase antibody [3F6] at 1:1000.

New Products