anti-FMO1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58710
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FMO1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FMO1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 334-363 of Human FMO1 (AFPFLDESVVKVEDGQASLYKYIFPAHLQK). |
| 偶联标记 | Un-conjugated |
| 別名 | Fetal hepatic flavin-containing monooxygenase 1; Dimethylaniline oxidase 1; Dimethylaniline monooxygenase [N-oxide-forming] 1; EC 1.14.13.8; FMO 1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FMO1 |
| 全名 | flavin containing monooxygenase 1 |
| 背景介绍 | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
| 生物功能 | This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. [UniProt] |
| 细胞定位 | Microsome membrane. Endoplasmic reticulum membrane. [UniProt] |
| 预测分子量 | 60 kDa |
检测图片 (1)
ARG58710 anti-FMO1 antibody WB image
Western blot: 50 µg of Rat Liver, 50 µg of Mouse liver, 50 µg of Rat kidney, 50 µg of Mouse kidney and 40 µg of SMMC whole cell lysate stained with ARG58710 anti-FMO1 antibody at 0.5 µg/ml.
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