anti-FMO4 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes FMO4
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FMO4
  • 抗原物种: Human
  • 抗原: Synthetic peptide corresponding to aa. 75-92 of Human FMO4 (HEDYPNFMNHEKFWDYLQ).
  • Brand:
CAT.NO. : ARG58703
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes FMO4
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称FMO4
抗原物种Human
抗原Synthetic peptide corresponding to aa. 75-92 of Human FMO4 (HEDYPNFMNHEKFWDYLQ).
偶联标记Un-conjugated
別名FMO2; Hepatic flavin-containing monooxygenase 4; FMO 4; Dimethylaniline oxidase 4; Dimethylaniline monooxygenase [N-oxide-forming] 4; EC 1.14.13.8
应用说明
应用建议
应用推荐稀释比
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
应用说明IHC-P: Antigen Retrieval: Heat mediated.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Thimerosal and 0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 226564 Mouse FMO4

GeneID: 2329 Human FMO4

GeneID: 246247 Rat FMO4

基因名称FMO4
全名flavin containing monooxygenase 4
背景介绍Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man. This results in a small subpopulation with reduced TMA N-oxidation capacity and causes fish odor syndrome (Trimethylaminuria). Three forms of the enzyme are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jan 2015]
生物功能This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. [UniProt]
细胞定位Microsome membrane. Endoplasmic reticulum membrane. [UniProt]
预测分子量63 kDa
检测图片 (2)
  • ARG58703 anti-FMO4 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat liver tissue stained with ARG58703 anti-FMO4 antibody.

  • ARG58703 anti-FMO4 antibody WB image

    Western blot: Rat liver, Mouse liver, SMMC, HEPA, A431 and MCF7 cell lysates stained with ARG58703 anti-FMO4 antibody.

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