anti-GCLC antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes GCLC |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GCLC |
| 抗原物种 | Human |
| 抗原 | Partial recombinant protein corresponding to aa. 437-637 of Human GCLC. |
| 偶联标记 | Un-conjugated |
| 別名 | GCS heavy chain; Gamma-glutamylcysteine synthetase; Gamma-ECS; GCL; GLCL; GCS; Glutamate--cysteine ligase catalytic subunit; EC 6.3.2.2; GLCLC |
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 72 kDa |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.025% Sodium azide and 2.5% BSA. |
| 抗菌剂 | 0.025% Sodium azide |
| 稳定剂 | 2.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # P19468 Rat Glutamate--cysteine ligase catalytic subunit Swiss-port # P48506 Human Glutamate--cysteine ligase catalytic subunit |
|---|---|
| 基因名称 | GCLC |
| 全名 | glutamate-cysteine ligase, catalytic subunit |
| 背景介绍 | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010] |
| 预测分子量 | 73 kDa |
ARG58032 anti-GCLC antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human lung cancer tissue stained with ARG58032 anti-GCLC antibody.
ARG58032 anti-GCLC antibody WB image
Western blot: 1) Rat brain, 2) Rat heart, 3) HeLa, 4) Rat PC12, 5) Rat NRK, 6) Mouse HEPA and 7) A549 cell lysates stained with ARG58032 anti-GCLC antibody.
ARG58032 anti-GCLC antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast cancer tissue stained with ARG58032 anti-GCLC antibody.
ARG58032 anti-GCLC antibody WB image
Western blot: 0.5 ng of recombinant Human protein stained with ARG58032 anti-GCLC antibody.
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