anti-GCNT3 antibody
CAT.NO. : ARG66593
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概述
产品描述 | Rabbit Polyclonal antibody recognizes GCNT3 |
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反应物种 | Hu |
应用 | ICC/IF, IHC-P |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | GCNT3 |
抗原物种 | Human |
抗原 | Synthetic peptide corresponding to aa. 200-280 of Human GCNT3. |
偶联标记 | Un-conjugated |
別名 | C2GnT-mucin type; C2GNT2; GNTM; EC 2.4.1.150; C2/4GnT; hC2GnT-M; C24GNT; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase; EC 2.4.1.102; C2GNTM; C2GnT-M |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol and 0.5% BSA |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O95395 Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminylt |
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基因名称 | GCNT3 |
全名 | glucosaminyl (N-acetyl) transferase 3, mucin type |
背景介绍 | This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009] |
生物功能 | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. [UniProt] |
细胞定位 | Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt] |
预测分子量 | 51 kDa |
翻译后修饰 | N-glycosylated. [UniProt] |
检测图片 (2)
ARG66593 anti-GCNT3 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG66593 anti-GCNT3 antibody. The picture on the right is blocked with the synthetic peptide.
ARG66593 anti-GCNT3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver carcinoma tissue stained with ARG66593 anti-GCNT3 antibody. The picture on the right is blocked with the synthetic peptide.
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