anti-GFAP antibody [SQab20213]
CAT.NO. : ARG66801
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概述
产品描述 | Recombinant Rabbit Monoclonal antibody [SQab20213] recognizes GFAP |
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反应物种 | Hu, Ms |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Monoclonal |
克隆号 | SQab20213 |
同位型 | IgG |
靶点名称 | GFAP |
抗原物种 | Human |
抗原 | Synthetic peptide within aa. 332-432 of Human GFAP. |
偶联标记 | Un-conjugated |
別名 | Glial fibrillary acidic protein; ALXDRD; GFAP |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C - 25°C) for 30 minutes. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein A. |
缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 40% Glycerol and 0.05% BSA |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | GFAP |
全名 | glial fibrillary acidic protein |
背景介绍 | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
生物功能 | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. [UniProt] |
细胞定位 | Cytoplasm. Note=Associated with intermediate filaments. [UniProt] |
预测分子量 | 50 kDa |
翻译后修饰 | Phosphorylated by PKN1. [UniProt] |
检测图片 (3)
ARG66801 anti-GFAP antibody [SQab20213] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human astrocytoma tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66801 anti-GFAP antibody [SQab20213].
ARG66801 anti-GFAP antibody [SQab20213] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human brain tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66801 anti-GFAP antibody [SQab20213].
ARG66801 anti-GFAP antibody [SQab20213] WB image
Western blot: Mouse Brain stained with ARG66801 anti-GFAP antibody [SQab20213] at 1:1000 dilution.
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