anti-GIT2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41201
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GIT2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GIT2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 450-510 of Human GIT2 (NP_476511.1). |
| 偶联标记 | Un-conjugated |
| 別名 | G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; ARF GTPase-activating protein GIT2; CAT-2; Cool-interacting tyrosine-phosphorylated protein 2; CAT2; ARF GAP GIT2 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A431 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q14161 Human ARF GTPase-activating protein GIT2 |
|---|---|
| 基因名称 | GIT2 |
| 全名 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| 背景介绍 | This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008] |
| 生物功能 | GTPase-activating protein for the ADP ribosylation factor family. [UniProt] |
| 预测分子量 | 85 kDa |
检测图片 (1)
ARG41201 anti-GIT2 antibody WB image
Western blot: 25 µg of A431 cell lysate stained with ARG41201 anti-GIT2 antibody at 1:1000 dilution.
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