anti-GPD1L antibody [14E2]
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![anti-GPD1L antibody [14E2]](/upload/image/products/ARG57070_WB_1.jpg)
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57070
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [14E2] recognizes GPD1L |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 14E2 |
| 同位型 | IgG1, kappa |
| 靶点名称 | GPD1L |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-351 of Human GPD1L. |
| 偶联标记 | Un-conjugated |
| 別名 | Glycerol-3-phosphate dehydrogenase 1-like protein; GPD1-L; EC 1.1.1.8 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8N335 Human Glycerol-3-phosphate dehydrogenase 1-like protein |
|---|---|
| 基因名称 | GPD1L |
| 全名 | glycerol-3-phosphate dehydrogenase 1-like |
| 背景介绍 | The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010] |
| 生物功能 | Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L. [UniProt] |
| 预测分子量 | 38 kDa |
检测图片 (2)
ARG57070 anti-GPD1L antibody [14E2] WB image
Western blot: 40 µg of 1) MCF7 cell lysate, 2) 293T cell lysate, 3) Jurkat cell lysate, 4) SW480 cell lysate, 5) PC3 cell lysate stained with ARG57070 anti-GPD1L antibody [14E2] at 1:500.
ARG57070 anti-GPD1L antibody [14E2] WB image
Western blot: 40 µg of 1) 293T cell lysate, 2) GPD1L Transfected 293T cell lysate stained with ARG57070 anti-GPD1L antibody [14E2] at 1:1000.
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