anti-GSTT1 antibody
CAT.NO. : ARG58916
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概述
产品描述 | Rabbit Polyclonal antibody recognizes GSTT1 |
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反应物种 | Hu |
应用 | FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | GSTT1 |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 7-34 of Human GSTT1. |
偶联标记 | Un-conjugated |
別名 | Glutathione S-transferase theta-1; EC 2.5.1.18; GST class-theta-1; Glutathione transferase T1-1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Human lung |
属性
形式 | Liquid |
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纯化 | Purification with Protein A and immunogen peptide. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
抗菌剂 | 0.09% (W/V) Sodium azide. |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | GSTT1 |
全名 | glutathione S-transferase theta 1 |
背景介绍 | The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
生物功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. [UniProt] |
细胞定位 | Cytoplasm. [UniProt] |
预测分子量 | 27 kDa |
检测图片 (2)
ARG58916 anti-GSTT1 antibody WB image
Western blot: 20 µg of Human lung lysate stained with ARG58916 anti-GSTT1 antibody at 1:2000 dilution.
ARG58916 anti-GSTT1 antibody FACS image
Flow Cytometry: 293 cells stained with ARG58916 anti-GSTT1 antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
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