anti-H Cadherin antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG55231
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes H Cadherin |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Chk |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | H Cadherin |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 589-617 (C-terminus) of Human H Cadherin. |
| 偶联标记 | Un-conjugated |
| 別名 | CDHH; H-cadherin; P105; Cadherin-13; Truncated cadherin; T-cad; Heart cadherin; T-cadherin |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human brain |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CDH13 |
| 全名 | cadherin 13 |
| 背景介绍 | This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011] |
| 生物功能 | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. [UniProt] |
| 细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. |
| 研究领域 | Cancer antibody; Signaling Transduction antibody |
| 预测分子量 | 78 kDa |
检测图片 (3)
ARG55231 anti-H Cadherin antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG55231 anti-H Cadherin antibody.
ARG55231 anti-H Cadherin antibody WB image
Western blot: 35 µg of Human brain lysate stained with ARG55231 anti-H Cadherin antibody at 1:1000 dilution.
ARG55231 anti-H Cadherin antibody FACS image
Flow Cytometry: MCF-7 cells stained with ARG55231 anti-H Cadherin antibody (bottom histogram) or without primary antibody control (top histogram), followed by incubation with FITC labelled secondary antibody.
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