anti-HDAC11 antibody
CAT.NO. : ARG41779
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概述
产品描述 | Rabbit Polyclonal antibody recognizes HDAC11 |
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反应物种 | Hu |
应用 | IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | HDAC11 |
抗原物种 | Human |
抗原 | Synthetic peptide of Human HDAC11. |
偶联标记 | Un-conjugated |
別名 | HD11; EC 3.5.1.98; Histone deacetylase 11 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | MCF7 | ||||||
实际分子量 | ~ 45 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | HDAC11 |
全名 | histone deacetylase 11 |
背景介绍 | This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009] |
生物功能 | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. [UniProt] |
细胞定位 | Nucleus. Note=Predominantly nuclear. [UniProt] |
预测分子量 | 39 kDa |
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