anti-Histone H2B acetyl (Lys5) antibody [RM455]
![anti-Histone H2B acetyl (Lys5) antibody [RM455]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG45027
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Product Details
概述
| 产品描述 | Rabbit monoclonal antibody recognizes Histone H2B acetyl (Lys5). |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 特异性 | This antibody reacts to Histone H2B acetylated at Lysine 5 (K5ac). No cross reactivity with other acetylated Lysines in histones. |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | RM455 |
| 同位型 | IgG |
| 靶点名称 | Histone H2B |
| 抗原物种 | Human |
| 抗原 | An acetyl-peptide corresponding to Acetyl-Histone H2B (Lys5). |
| 偶联标记 | Un-conjugated |
| 別名 | H2BC3; H2B Clustered Histone 3; H2B/F; HIST1H2BB; H2BFF; Histone Cluster 1 H2B Family Member B; H2B Histone Family, Member F; Histone Cluster 1, H2bb; Histone H2B Type 1-B; Histone 1, H2bb; Histone H2B.1; Histone H2B.F; H2B-Clustered Histone 3; H2B.1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 稳定剂 | 50% Glycerol, 1% BSA and 0.09% |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | H2BC3 |
| 全名 | H2B Clustered Histone 3 |
| 背景介绍 | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] |
| 生物功能 | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [Uniprot] |
| 细胞定位 | Chromosome, Nucleosome core, Nucleus. [Uniprot] |
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