anti-Histone H2B type 2-K1 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes Histone H2B type 2-K1
  • 反应物种: Hu
  • 应用: IHC-P, IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: Histone H2B type 2-K1
  • 抗原物种: Human
  • 抗原表位: GTKAVTKYTS
  • Brand:
CAT.NO. : ARG44839
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes Histone H2B type 2-K1
反应物种Hu
应用IHC-P, IP
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称Histone H2B type 2-K1
抗原物种Human
抗原表位GTKAVTKYTS
偶联标记Un-conjugated
別名H2BK1; H2B.K Variant Histone 1; H2BE1 H2B.E Variant Histone 1; Histone H2B Type 2-K1; Histone H2B Type 2-E1; Novel Histone H2B-Like Protein
应用说明
应用建议
应用推荐稀释比
IHC-P1:250 - 1:500
IP1:100
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
抗菌剂0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称H2BK1
全名H2B.K Variant Histone 1
背景介绍Predicted to enable DNA binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022]
生物功能Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]
细胞定位Chromosome, Nucleosome core, Nucleus. [UniProt]
翻译后修饰Glycoprotein, Hydroxylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation. [UniProt]
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