anti-HLA A2 antibody [BB7.2] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [BB7.2] recognizes HLA A2
反应物种: Hu
应用: FACS
特异性: The clone BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
宿主: Mouse
克隆: Monoclonal
克隆号: BB7.2
同位型: IgG2b
靶点名称: HLA A2

CAT.NO. : ARG53935

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Size:

100 tests

Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [BB7.2] recognizes HLA A2
反应物种	Hu
应用	FACS
特异性	The clone BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
宿主	Mouse
克隆	Monoclonal
克隆号	BB7.2
同位型	IgG2b
靶点名称	HLA A2
抗原	HLA-A2 solubilised by papain_x000D_
偶联标记	PE
別名	MHC class I antigen A*1; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain

应用说明

应用建议

应用	推荐稀释比
FACS	20 µl / 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化说明	The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
缓冲液	PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂	15 mM Sodium azide
稳定剂	0.2% (w/v) high-grade protease free BSA
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3105 Human HLA-A Swiss-port # P30443 Human HLA class I histocompatibility antigen, A-1 alpha chain
基因名称	HLA-A
全名	major histocompatibility complex, class I, A
背景介绍	HLA-A2 (44 kDa) is the most frequent HLA-A allele in human ethnic populations. HLA-A, together with HLA-B and HLA-C, represent human HLA class I major histocompatibility (MHC) antigens. These intrinsic membrane glycoproteins are expressed on nucleated cells and noncovalently associate with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence._x000D_
生物功能	Involved in the presentation of foreign antigens to the immune system. [UniProt]
研究领域	Immune System antibody
预测分子量	40 kDa
翻译后修饰	Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).

检测图片 (1)

ARG53935 anti-HLA A2 antibody [BB7.2] (PE) FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG53935 anti-HLA A2 antibody [BB7.2] (PE).

参考文献

STING agonist diABZI enhances the cytotoxicity of T cell towards cancer cells

FACS / Human

Ling Wang et al.
Cell Death Dis., (2024)