anti-hnRNP U antibody
CAT.NO. : ARG54077
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概述
产品描述 | Mouse Monoclonal antibody recognizes HNRNPU |
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反应物种 | Hu |
应用 | WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | hnRNP U |
抗原物种 | Human |
抗原 | Purified recombinant human hnRNP U protein fragments expressed in E.coli. |
偶联标记 | Un-conjugated |
別名 | U21.1; p120; hnRNP U; Heterogeneous nuclear ribonucleoprotein U; SAFA; HNRPU; SAF-A; pp120; Scaffold attachment factor A |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
实际分子量 | 110 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified |
缓冲液 | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
抗菌剂 | 0.2% Sodium azide |
稳定剂 | 50% Glycerol |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q00839 Human Heterogeneous nuclear ribonucleoprotein U |
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基因名称 | HNRNPU |
全名 | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
背景介绍 | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. |
生物功能 | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity). [UniProt] |
细胞定位 | Nucleus. Cytoplasm. Cell surface. |
研究领域 | Gene Regulation antibody |
预测分子量 | 91 kDa |
翻译后修饰 | Extensively phosphorylated. Arg-739 is dimethylated, probably to asymmetric dimethylarginine. Citrullinated by PADI4. |
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