anti-HPRT1 antibody
CAT.NO. : ARG59709
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概述
产品描述 | Rabbit Polyclonal antibody recognizes HPRT1 |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P, IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | HPRT1 |
抗原物种 | Human |
抗原 | Synthetic peptide derived from Human HPRT1. |
偶联标记 | Un-conjugated |
別名 | EC 2.4.2.8; Hypoxanthine-guanine phosphoribosyltransferase; HGPRTase; HGPRT; HPRT |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
实际分子量 | 25 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P00492 Human Hypoxanthine-guanine phosphoribosyltransferase Swiss-port # P27605 Rat Hypoxanthine-guanine phosphoribosyltransferase |
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基因名称 | HPRT1 |
全名 | hypoxanthine phosphoribosyltransferase 1 |
背景介绍 | The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009] |
生物功能 | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. [UniProt] |
细胞定位 | Cytoplasm. [UniProt] |
预测分子量 | 25 kDa |
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