anti-HSD3B1 + HSD3B2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG59769
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HSD3B1 + HSD3B2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HSD3B1 + HSD3B2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-287 of Human HSD3B2 (NP_000189.1). |
| 偶联标记 | Un-conjugated |
| 別名 | 3-beta-HSD adrenal and gonadal type; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II; HSDB; EC 1.1.1.145; HSD3B; EC 5.3.3.1; 3-beta-HSD II; 5; Progesterone reductase; SDR11E2; Delta-5-3-ketosteroid isomerase; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse brain and U937 | ||||||
| 实际分子量 | 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P26149 Mouse 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 Swiss-port # P26439 Human 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 |
|---|---|
| 基因名称 | HSD3B2 |
| 全名 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| 背景介绍 | The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] |
| 生物功能 | 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. [UniProt] |
| 预测分子量 | 42 kDa |
检测图片 (2)
ARG59769 anti-HSD3B1 + HSD3B2 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG59769 anti-HSD3B1 + HSD3B2 antibody.
ARG59769 anti-HSD3B1 + HSD3B2 antibody WB image
Western blot: 25 µg of Mouse brain and U937 cell lysate stained with ARG59769 anti-HSD3B1 + HSD3B2 antibody at 1:1000 dilution.
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