anti-HSPA2 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes HSPA2
  • 反应物种: Hu, Ms
  • 应用: IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG2a
  • 靶点名称: HSPA2
  • 抗原物种: Human
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG44676
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes HSPA2
反应物种Hu, Ms
应用IP
宿主Mouse
克隆Monoclonal
同位型IgG2a
靶点名称HSPA2
抗原物种Human
偶联标记Un-conjugated
別名Heat shock 70 kDa protein 2; Heat shock-related 70 kDa protein 2; HSP70-2; HSP70-3
应用说明
应用建议
应用推荐稀释比
IP10 µg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15512 Mouse HSPA2

GeneID: 3306 Human HSPA2

Swiss-port # P17156 Mouse Heat shock-related 70 kDa protein 2

Swiss-port # P54652 Human Heat shock-related 70 kDa protein 2

基因名称HSPA2
全名heat shock 70kDa protein 2
背景介绍Hsp70, one class of stress proteins, is comprised of multiple members, all of which bind ATP in vitro, but are localized within different intracellular compartments. These include: a) the constitutive Hsc70 (or cognate) present within the cytosol/nucleus; b) the highly stress-inducible Hsp70 present within the cytosol/ nucleus/nucleolus; c) the constitutive glucose regulated 78 kDa (or BiP) protein present within the lumen of the endoplasmic reticulum; and d) the glucose regulated 75 kDa protein present within the mitochondria. Hsp70 is typically not expressed in the cell under normal growth conditions, but is expressed at high levels in the cell experiencing stress. Consequently, detection of Hsp70 using an antibody specific for the inducible form is quite useful in ascertaining whether a stress response has occurred in the cell. It should be noted, however, that there is a constitutive level of Hsp70 expression in some cell types such as primates, e.g., human and monkey. Nevertheless increased expression of Hsp70 is observed in such cells following stress.
翻译后修饰The N-terminal may be partly blocked. [UniProt]
检测图片 (1)
  • ARG44676 anti-HSPA2 antibody IP image

    Immunoprecipitation: Mouse Testis lysate immunoprecipitated with 2.5 µg of ARG44676 anti-HSPA2 antibody.

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