anti-HSPA2 antibody
CAT.NO. : ARG44676
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概述
产品描述 | Mouse Monoclonal antibody recognizes HSPA2 |
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反应物种 | Hu, Ms |
应用 | IP |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG2a |
靶点名称 | HSPA2 |
抗原物种 | Human |
偶联标记 | Un-conjugated |
別名 | Heat shock 70 kDa protein 2; Heat shock-related 70 kDa protein 2; HSP70-2; HSP70-3 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P17156 Mouse Heat shock-related 70 kDa protein 2 Swiss-port # P54652 Human Heat shock-related 70 kDa protein 2 |
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基因名称 | HSPA2 |
全名 | heat shock 70kDa protein 2 |
背景介绍 | Hsp70, one class of stress proteins, is comprised of multiple members, all of which bind ATP in vitro, but are localized within different intracellular compartments. These include: a) the constitutive Hsc70 (or cognate) present within the cytosol/nucleus; b) the highly stress-inducible Hsp70 present within the cytosol/ nucleus/nucleolus; c) the constitutive glucose regulated 78 kDa (or BiP) protein present within the lumen of the endoplasmic reticulum; and d) the glucose regulated 75 kDa protein present within the mitochondria. Hsp70 is typically not expressed in the cell under normal growth conditions, but is expressed at high levels in the cell experiencing stress. Consequently, detection of Hsp70 using an antibody specific for the inducible form is quite useful in ascertaining whether a stress response has occurred in the cell. It should be noted, however, that there is a constitutive level of Hsp70 expression in some cell types such as primates, e.g., human and monkey. Nevertheless increased expression of Hsp70 is observed in such cells following stress. |
翻译后修饰 | The N-terminal may be partly blocked. [UniProt] |
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