anti-Human IgE antibody [BE5]
![anti-Human IgE antibody [BE5]](/upload/image/products/ARG65416_FACS_1_210_205.jpg)
![anti-Human IgE antibody [BE5]](/upload/image/products/ARG65416_FACS_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG65416
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [BE5] recognizes Human IgE |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS |
| 特异性 | The clone BE5 reacts with human IgE; it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | BE5 |
| 同位型 | IgG1 |
| 靶点名称 | Human IgE |
| 抗原物种 | Human |
| 抗原 | Purified human IgE. |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A affinity purified. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion. |
| 研究领域 | Immune System antibody |
检测图片 (1)
ARG65416 anti-Human IgE antibody [BE5] FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG65416 anti-Human IgE antibody [BE5], followed by incubation with APC labeled Goat anti-Mouse secondary antibody.
参考文献
克隆号文献
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.
FACS / Human
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