anti-IFN gamma antibody [CC330]
CAT.NO. : ARG22850
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概述
产品描述 | Mouse Monoclonal antibody [CC330] recognizes IFN gamma |
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反应物种 | Bov, Goat, Sheep |
应用 | ELISA, ELISPOT, FACS |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | CC330 |
同位型 | IgG1 |
靶点名称 | IFN gamma |
抗原物种 | Bovine |
抗原 | Recombinant Bovine IFN-gamma. |
偶联标记 | Un-conjugated |
別名 | IFN-gamma; Interferon gamma; Immune interferon; IFG; IFI |
应用说明
应用建议 |
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应用说明 | FACS: Membrane permeabilisation is required for this application. FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl whole blood. ELISA: This clone may be used in a sandwich ELISA. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein A. |
缓冲液 | PBS and 0.09% Sodium azide |
抗菌剂 | 0.09% Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | IFNG |
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全名 | interferon, gamma |
背景介绍 | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015] |
生物功能 | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. [UniProt] |
产品亮点 | Related products: IFN gamma antibodies; IFN gamma ELISA Kits; IFN gamma Duos / Panels; IFN gamma recombinant proteins; Anti-Mouse IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
预测分子量 | 19 kDa |
翻译后修饰 | Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. |
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