anti-IgG1 antibody [RM117]
![anti-IgG1 antibody [RM117]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG45016
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Product Details
概述
| 产品描述 | Rabbit Monoclonal antibody [RM117] recognizes IgG1. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, ICC/IF, IHC-P |
| 特异性 | This antibody reacts to the heavy chain of human IgG1. RM117 does not cross react to any other IgG subclasses (IgG2, IgG3, or IgG4), and shows no cross reactivity to IgM, IgA, IgD, IgE. RM117 does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | RM117 |
| 同位型 | IgG |
| 靶点名称 | IgG1 |
| 抗原物种 | Human |
| 抗原 | Peptide corresponding to the hinge region of Human IgG1 |
| 目标Ig | IgG1 |
| 偶联标记 | Un-conjugated |
| 別名 | IGHG1; Immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Constant Region Of Heavy Chain Of IgG1; Immunoglobulin Heavy Constant Gamma 1; Immunoglobulin Gamma 1 (Gm Marker); Ig Gamma-1 Chain C Region KOL; Ig Gamma-1 Chain C Region NIE; Ig Gamma-1 Chain C Region EU; Ig Gamma-1 Chain C Region |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 缓冲液 | PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide |
|---|---|
| 抗菌剂 | 0.09% sodium azide |
| 稳定剂 | 50% Glycerol, 1% BSA and 0.09% |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IGHG1 |
| 全名 | Immunoglobulin Heavy Constant Gamma 1 (G1m Marker) |
| 背景介绍 | Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to act upstream of or within several processes, including immunoglobulin mediated immune response; positive regulation of hypersensitivity; and positive regulation of phagocytosis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. [Uniprot] |
| 细胞定位 | Cell membrane, Immunoglobulin, Membrane, Secreted. [Uniprot] |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [Uniprot] |
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