anti-IL13 Receptor alpha 1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG55710
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IL13 Receptor alpha 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL13 Receptor alpha 1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 207-238 (C-terminus) of Human IL13 Receptor alpha 1. |
| 偶联标记 | Un-conjugated |
| 別名 | CD antigen CD213a1; Interleukin-13 receptor subunit alpha-1; CD213A1; IL-13R-alpha-1; CT19; IL-13R subunit alpha-1; IL-13Ra; IL-13 receptor subunit alpha-1; IL-13RA1; Cancer/testis antigen 19; NR4 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Raji |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) sodium azide. |
| 抗菌剂 | 0.09% (W/V) sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P78552 Human Interleukin-13 receptor subunit alpha-1 |
|---|---|
| 基因名称 | IL13RA1 |
| 全名 | interleukin 13 receptor, alpha 1 |
| 背景介绍 | The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein |
| 预测分子量 | 49 kDa |
检测图片 (1)
ARG55710 anti-IL13 Receptor alpha 1 antibody WB image
Western blot: 35 µg of Raji cell lysate stained with ARG55710 anti-IL13 Receptor alpha 1 antibody at 1:1000 dilution.
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