anti-IL33R / ST2 antibody
产品描述 | Rabbit Polyclonal antibody recognizes IL33R / ST2 |
---|---|
反应物种 | Hu, Ms |
应用 | ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | IL33R / ST2 |
抗原物种 | Mouse |
抗原 | Synthetic peptide (16 aa) within aa. 40-90 of Mouse ST2. This peptide is common to all three known ST2 isoforms. |
偶联标记 | Un-conjugated |
別名 | IL33R; DER4; ST2V; T1; Interleukin-1 receptor-like 1; FIT-1; ST2; ST2L; Protein ST2 |
应用建议 |
| ||||||||
---|---|---|---|---|---|---|---|---|---|
应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | 293 cells |
形式 | Liquid |
---|---|
纯化 | Affinity purification with immunogen. |
缓冲液 | PBS and 0.02% Sodium azide |
抗菌剂 | 0.02% Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
数据库连接 | |
---|---|
基因名称 | Il1rl1 |
全名 | interleukin 1 receptor-like 1 |
背景介绍 | The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
生物功能 | Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. [UniProt] |
细胞定位 | Cell membrane; Single-pass type I membrane protein. Isoform B: Secreted |
预测分子量 | 63 kDa |
ARG56878 anti-IL33R / ST2 antibody WB image
Western blot: 293 cell lysate stained with ARG56878 anti-IL33R / ST2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
ARG56878 anti-IL33R / ST2 antibody IHC-P image
Immunohistochemistry: Human lung cancer tissue stained with ARG56878 anti-IL33R / ST2 antibody at 5 µg/ml.
ARG56878 anti-IL33R / ST2 antibody IHC image
Immunohistochemistry: Human lung cancer tissue stained with ARG56878 anti-IL33R / ST2 antibody at 5 µg/ml.
ARG56878 anti-IL33R / ST2 antibody IHC-P image
Immunohistochemistry: Human liver tissue stained with ARG56878 anti-IL33R / ST2 antibody at 5 µg/ml.
ARG56878 anti-IL33R / ST2 antibody ICC/IF image
Immunofluorescence: Mouse kidney cells stained with ARG56878 anti-IL33R / ST2 antibody at 20 µg/ml.