anti-IMPAD1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes IMPAD1
  • 反应物种: Hu, Ms, Rat
  • 应用: FACS, ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IMPAD1
  • 抗原物种: Human
  • 抗原: Human IMPAD1 recombinant protein
  • Brand:
CAT.NO. : ARG44453
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes IMPAD1
反应物种Hu, Ms, Rat
应用FACS, ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称IMPAD1
抗原物种Human
抗原Human IMPAD1 recombinant protein
偶联标记Un-conjugated
別名BPNT2; 3'(2'), 5'-Bisphosphate Nucleotidase 2; IMPA3; GPAPP; Golgi-Resident Adenosine 3',5'-Bisphosphate 3'-Phosphatase; IMPAD1; Inositol Monophosphatase Domain-Containing Protein 1; Inositol Monophosphatase Domain Containing 1; Phosphoadenosine Phosphate 3'-Nucleotidase; Golgi-Resident Nucleotide Phosphatase; Myo-Inositol Monophosphatase A3; Golgi-Resident PAP Phosphatase
应用说明
应用建议
应用推荐稀释比
FACS1-3 µg/1x10^6
ICC/IF5 µg/ml
IHC-P1-2 µg/ml
WB0.1-0.25 µg/ml
应用说明The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂0.05% Sodium azide
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 242291 Mouse IMPAD1

GeneID: 312952 Rat IMPAD1

GeneID: 54928 Human IMPAD1

基因名称BPNT2
全名3'(2'), 5'-Bisphosphate Nucleotidase 2
背景介绍This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.
生物功能Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I1P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4.
细胞定位Golgi apparatus, Membrane
预测分子量39 kDa
翻译后修饰Acetylation, Glycoprotein
检测图片 (7)
  • ARG44453 anti-IMPAD1 antibody IHC-P image

    Immunohistochemistry: Human colon adenocarcinomastained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.

  • ARG44453 anti-IMPAD1 antibody ICC/IF image

    Immunofluorescence: SiHa stained with ARG44453 anti-IMPAD1 antibody at 5 μg/mL dilution.

  • ARG44453 anti-IMPAD1 antibody WB image

    Western blot: A549, U251 and HepG2 stained with ARG44453 anti-IMPAD1 antibody at 0.5 μg/mL dilution.

  • ARG44453 anti-IMPAD1 antibody FACS image

    Flow Cytometry: HepG2 stained with ARG44453 anti-IMPAD1 antibody at 1 μg/10^6 cells dilution.

  • ARG44453 anti-IMPAD1 antibody IHC-P image

    Immunohistochemistry: Rat brain stained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.

  • ARG44453 anti-IMPAD1 antibody IHC-P image

    Immunohistochemistry: Mouse brain stained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.

  • ARG44453 anti-IMPAD1 antibody IHC-P image

    Immunohistochemistry: Human meningioma stained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.

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