anti-IMPAD1 antibody
产品描述 | Rabbit Polyclonal antibody recognizes IMPAD1 |
---|---|
反应物种 | Hu, Ms, Rat |
应用 | FACS, ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | IMPAD1 |
抗原物种 | Human |
抗原 | Human IMPAD1 recombinant protein |
偶联标记 | Un-conjugated |
別名 | BPNT2; 3'(2'), 5'-Bisphosphate Nucleotidase 2; IMPA3; GPAPP; Golgi-Resident Adenosine 3',5'-Bisphosphate 3'-Phosphatase; IMPAD1; Inositol Monophosphatase Domain-Containing Protein 1; Inositol Monophosphatase Domain Containing 1; Phosphoadenosine Phosphate 3'-Nucleotidase; Golgi-Resident Nucleotide Phosphatase; Myo-Inositol Monophosphatase A3; Golgi-Resident PAP Phosphatase |
应用建议 |
| ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
形式 | Liquid |
---|---|
纯化 | Affinity purification with immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
数据库连接 | |
---|---|
基因名称 | BPNT2 |
全名 | 3'(2'), 5'-Bisphosphate Nucleotidase 2 |
背景介绍 | This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. |
生物功能 | Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I1P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4. |
细胞定位 | Golgi apparatus, Membrane |
预测分子量 | 39 kDa |
翻译后修饰 | Acetylation, Glycoprotein |
ARG44453 anti-IMPAD1 antibody IHC-P image
Immunohistochemistry: Human colon adenocarcinomastained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.
ARG44453 anti-IMPAD1 antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG44453 anti-IMPAD1 antibody at 5 μg/mL dilution.
ARG44453 anti-IMPAD1 antibody WB image
Western blot: A549, U251 and HepG2 stained with ARG44453 anti-IMPAD1 antibody at 0.5 μg/mL dilution.
ARG44453 anti-IMPAD1 antibody FACS image
Flow Cytometry: HepG2 stained with ARG44453 anti-IMPAD1 antibody at 1 μg/10^6 cells dilution.
ARG44453 anti-IMPAD1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.
ARG44453 anti-IMPAD1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.
ARG44453 anti-IMPAD1 antibody IHC-P image
Immunohistochemistry: Human meningioma stained with ARG44453 anti-IMPAD1 antibody at 2 μg/mL dilution.