anti-Involucrin antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Involucrin
  • 反应物种: Hu
  • 预测物种: Rat
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Involucrin
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG59359
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Involucrin
反应物种Hu
预测物种Rat
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Involucrin
抗原物种Human
抗原Synthetic peptide derived from Human Involucrin.
偶联标记Un-conjugated
別名Involucrin
应用说明
应用建议
应用推荐稀释比
FACS1:10
IHC-P1:50 - 1:200
WB1:1000 - 1:5000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照A431
实际分子量120 ~ 130 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3713 Human IVL

Swiss-port # P07476 Human Involucrin

基因名称IVL
全名involucrin
背景介绍Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]
生物功能Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. [UniProt]
细胞定位Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope. [UniProt]
预测分子量68 kDa
翻译后修饰Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. [UniProt]
检测图片 (2)
  • ARG59359 anti-Involucrin antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human tonsil stained with ARG59359 anti-Involucrin antibody.

  • ARG59359 anti-Involucrin antibody WB image

    Western blot: A431 cell lysate stained with ARG59359 anti-Involucrin antibody.

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