anti-Involucrin antibody
CAT.NO. : ARG59359
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概述
产品描述 | Rabbit Polyclonal antibody recognizes Involucrin |
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反应物种 | Hu |
预测物种 | Rat |
应用 | FACS, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Involucrin |
抗原物种 | Human |
抗原 | Synthetic peptide derived from Human Involucrin. |
偶联标记 | Un-conjugated |
別名 | Involucrin |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | A431 | ||||||||
实际分子量 | 120 ~ 130 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | IVL |
全名 | involucrin |
背景介绍 | Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008] |
生物功能 | Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. [UniProt] |
细胞定位 | Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope. [UniProt] |
预测分子量 | 68 kDa |
翻译后修饰 | Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. [UniProt] |
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