anti-ITGB1BP2 / Melusin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 偶联标记:
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Brand:
CAT.NO. : ARG44686
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes ITGB1BP2 / Melusin |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | ITGB1BP2 / Melusin |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | CHORDC3; Integrin beta-1-binding protein 2; MSTP015; ITGB1BP; Melusin; MELUSIN |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ITGB1BP2 |
| 全名 | integrin beta 1 binding protein (melusin) 2 |
| 背景介绍 | This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. [provided by RefSeq, May 2017] |
| 生物功能 | May play a role during maturation and/or organization of muscles cells. [UniProt] |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
检测图片 (2)
ARG44686 anti-ITGB1BP2 / Melusin antibody WB image
Western blot: Rat skeletal stained with ARG44686 anti-ITGB1BP2 / Melusin antibody at 1 µg/mL dilution.
ARG44686 anti-ITGB1BP2 / Melusin antibody IP image
Immunoprecipitation: Rat skeletal lysate immunoprecipitated with 2.5 µg of ARG44686 anti-ITGB1BP2 / Melusin antibody.
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