anti-Kir4.1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG23724
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Kir4.1 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Kir4.1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human Kir4.1 |
| 偶联标记 | Un-conjugated |
| 別名 | KCNJ13-PEN; BIRK-10; KIR4.1; ATP-sensitive inward rectifier potassium channel 10; SESAME; Inward rectifier K; Potassium channel, inwardly rectifying subfamily J member 10; ATP-dependent inwardly rectifying potassium channel Kir4.1; KIR1.2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.09% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P49655 Rat ATP-sensitive inward rectifier potassium channel 10 Swiss-port # P78508 Human ATP-sensitive inward rectifier potassium channel 10 |
|---|---|
| 基因名称 | KCNJ10 |
| 全名 | potassium channel, inwardly rectifying subfamily J, member 10 |
| 背景介绍 | This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (2)
ARG23724 anti-Kir4.1 antibody ICC/IF image
Immunofluorescence: Human colon carcinoma cell line (RKO) fixed by 4% Formaldehyde for 15 min at RT. Primary Antibody: ARG23724 anti-Kir4.1 antibody (green) at 1:100 for 60 min at RT. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Primary antibodies. (D) Composite.
ARG23724 anti-Kir4.1 antibody WB image
Western blot: 15 µg of Rat liver cell lysates stained with ARG23724 anti-Kir4.1 antibody at 1:1000 for 2 hours at RT.
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